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Description
It is due to an autoimmune disease
By donating its methyl group, SAM is converted first to S-adenosyl homocysteine (SAH) and then to homocysteine

Symptoms of Low Levels of Cobalamin Include: anemia, nerve damage (burning, tingling, weakness or numbness in hands and feet), difficulty in sensing vibration, unsteadiness and psychological side effects

EDTA plasma rather than serum for B12, folate and ferritin estimations
