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A skin biopsy stays at Level IV whether it shows a benign or malignant result, so procedure code 88305 is assigned at accession by specimen type

The mainstay of treatment is an aggressive surgical approach with negative margins (R0 resection) followed by adjuvant radiotherapy for tumors with high grade, large size, and positive margins and the addition of chemotherapy for those who can tolerate it [3]
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Melanotan-2 may be relevant when the hypothesis intentionally includes broader melanocortin receptor biology
