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However, due to the cost and the difficulty in guaranteeing the availability of the equipment, the energy intake is often estimated at 30kcal/kg of ideal body weight or by using various prediction formulas such as the HarrisBenedict equation, suggested by the European Society of Clinical Nutrition and Metabolism, as used in this study.9 Metabolic decompensation, experienced by MELAS patients, can occur for different reasons

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Loads in the 75-85% range may suffice for less-trained individuals, but as training advances, high intensity is key for continual strength improvement

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