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For example, zinc is a crucial component of the SOD enzyme system, while lead is involved in the electron transport chain of ROS
Thiazolidinediones (TZD) counteract insulin resistance through its binding to PPAR, which activates the transcription of antioxidant-associated genes, including superoxide Dismutase1 (SOD) and catalase (CAT) (Khoo et al., 2013)

These genetic differences underscore the importance of considering breed as a factor when evaluating bile acid dynamics and its implications for disease diagnosis and treatment
Smith, E.R
