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Description
The intermediate form of the enzyme is further reduced by the formation of an intra-molecular disulfide bond between the two active site cysteines, leaving the enzyme in an oxidized form, from which the vicinal thiols are regenerated by the FAD(H)-intermediated hydride transfer from NAD(P)H
Moreover, lactate metabolism contributes to NADPH production through TCA cycle-linked pathways, particularly those catalyzed by malic enzyme 1 (ME1) and isocitrate dehydrogenase 1 (IDH1) (94,96)
Storage Store at controlled room temperature
This can lead to fatigue, shortness of breath, dizziness, and pale skin
