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The peptide P4-9 did potentiate the effect of antibiotic novobiocin in a process the authors referred to as Post-Antibiotic Effect-associated Permeabilization. Similarly, administration of other antibiotics such as macrolide, cephalosporins, ciprofloxacin, rifampin, and fosfomycin after the withdrawal of P4-9 also showed Post-Antibiotic Effect-associated Permeabilization at a varying magnitude