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Pegylation alone does not allow nanoparticles to cross the BBB, as it has been shown in multiple studies [87,123,145,146]

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Proline suppresses rubisco activity by dissociating small subunits from holoenzyme

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demonstrates that STAT3 binds to consensus DNA response elements in the promoters of the GPX4, SLC7A11, and regulates their expression, thereby establishing a negative STAT3-ferroptosis regulatory axis in gastric cancer (Ouyang et al., 2022)

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