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In a doseresponse meta-analysis (48), increasing 5 mg -carotene daily reduced 10% risk of ARC, and increasing 10 mg lutein or zeaxanthin daily reduced 19% risk of ARC

The 0.25mg starter dose is designed to minimise side effects

10.1002/ame2.12227 126 ZhouZ.ZhongW.LinH.HuangP.MaN.ZhangY.et al (2017)

Colannino, G
