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Description
COPD was defined on the basis of preoperative lung function: FEV1/FVC less than 70% and no reversibility (bronchodilatation effect less than 12%) according to GOLD criteria [23]
The increase in ROS levels is due to changes in the intracellular redox balance of cells, and the failure of antioxidant mechanisms to eliminate ROS production can promote this [6]

Lo Bello M, Nuccetelli M, Chiessi E, Lahm A, Mazzetti AP, Battistoni A, et al

SGBS cells were kindly provided by Martin Wabitsch and Raffaele de Caterina