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In contrast, astrocytes exhibit lower expression of pyruvate dehydrogenase (Laughton et al., 2007), which limits oxidative phosphorylation (Itoh et al., 2003) and reduces pyruvate utilization efficiency in the TCA cycle (Rahman et al., 2020)

doi: 10.3109/08923973.2013.790413 156 ChengHLYenGCHuangSCChenSCHsuCL

A clinical study enrolling 150 IBD patients also provided empirical evidence for the significant correlation between leaky gut and decreased BMD (66)
B6 is required for neurotransmitter synthesis
