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When B12 levels become problematic: High-dose supplementation (particularly doses exceeding 1,000 micrograms daily) Frequent B12 injections without medical supervision Underlying conditions affecting B12 metabolism Concurrent use of multiple B12-containing supplements The NHS does not set an upper safe limit for vitamin B12 because harmful effects from excessive intake have not been definitively established

By working together, you and your provider can adjust your schedule to match your bodys evolving needs, ensuring your answer to "how often should I get B12 shots?" is always the right one for you

A phase I/IIa study of the CD38 antibody MOR202 in combination with pomalidomide or lenalidomide in patients with relapsed or refractory multiple myeloma

Of course, older adults, people over age 50 in particular, tend to have the lowest B12 levels, though vegetarians and those who have undergone gastric bypass surgery are also at a higher risk