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These results suggest that MTHFR deficiency coupled with a low-quality high-fat diet may increase the risk of developing non-alcoholic fatty liver disease (NAFLD) due to disrupted methylation capacity, lipid metabolism, and inflammatory responses [24]

doi: 10.1007/s40257-013-0036-6

Tena-Solsona, M., Wanzke, C., Riess, B., Bausch, A

The pBos-SMC1-GFP, pBos-SMC3-GFP, and pBos-RAD21-GFP constructs were generated by replacing the H2B coding sequence with PCR-amplified coding sequences of SMC1, SMC3, and RAD21, respectively
