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In euthyroid status, 80% of brain T3 is derived from central deiodination, and 20% is derived from peripheral deiodination (Irachi et al
[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Son D.O., Satsu H., Kiso Y., Shimizu M
There is no definitive treatment, and management is mainly supportive (mouth rinses, analgesics, coating agents)
In an in vivo study utilizing TIGAR conditional knockout mice, TIGAR loss impaired tumor formation in intestinal colon cancer generated by the loss of the tumor suppressor APC
