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Therefore, both fluorescence and MR imaging reveal that our PEGylated hollow MnO 2 nanoshells with drug loading on one hand exhibit efficient passive tumor homing after systemic administration via the enhanced permeability and retention (EPR) effect, on the hand other could be gradually decomposed into free ions and molecules with rapid renal excretion

We acknowledge support from the Biomedicum Imaging Core Facility at Karolinska Institutet, supported by the Knut and Alice Wallenberg Foundation, the Eukaryotic Single Cell Genomics Facility at the Science for Life Laboratory, Sweden, for the scRNA-seq experiments

Molecular mechanisms underlying delayed apoptosis in neutrophils from multiple trauma patients with and without sepsis