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Exposure of proteins to HOCl results in a broad range of modifications that have been very recently summarized in an excellent review by Hawkins [225] and only a short overview, based mostly on experimental data from the Davies and Hawkins groups, will be given here and in Fig

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Molecular patterns associated with microbes (MAMPs), which we can detect circulating in IBD, might activate immune responses as well as T cells, osteocytes, osteoblasts, and osteoclasts located in the bone marrow, which leads to low bone formation and high resorption (240)