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2.5.1 Basic science research In T2DM, impaired autophagy in pancreatic cells leads to the accumulation of metabolic products and damaged organelles (Xxxx et al., 2022)

Besides the effects of vitamin C in KRAS/BRAF -mutated CRC, other studies have demonstrated that the anti-cancer potential of vitamin C might be particularly efficient in tumors driven by the HIF1 signaling pathway [46]

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Thus, the identification of novel therapeutic targets and strategies is essential
