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CD38 in Immune Metabolism and Tumor Biology Age-related diseases such as cancer provide an interesting context for considering ways in which immune cells are modulated by the tumor microenvironment as well as targeted by immune-based therapies

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Because of this and the fact that the body only needs a small amount of vitamin B12 each day, it can take up to a year or even longer for an inadequate vitamin B12 to manifest as an apparent deficiency