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In case of mutations affecting the function of the bile salt transporter, but especially when the FGF19-driven negative feedback pathway is defective, this leads to bile acid diarrhea type 2 (168)

Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties
4.3 The potential of peptide-based redevelopment of dendritic cell vaccines After considerable endeavors, sipuleucel-T stands alone as the immunotherapeutic agent that has yielded a significant survival benefit in a randomized Phase 3 clinical trial (Kantoff et al., 2010)

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