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People with diabetes face a 1.5- to 4-fold increased risk of both common and severe infections, and infections remain the leading cause of morbidity and mortality

Nanoparticles based on system X c /GSH/GPX4 axis for treatment of drug-resistant solid tumors The current ferroptosis inducers are mainly small molecules targeting the different targets in the System X c /GSH/GPX4 axis

Circulating monocytes from RA patients produce elevated levels of IL-1 and IL-6 upon in vitro stimulation (69), IL-6 contributes to joint destruction (70), while IL-1 promotes osteoclastogenesis, induces matrix metalloproteinase (MMP) expression in chondrocytes, and initiates synoviocyte proliferation (71)