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TMAO may be a potential biomarker of disease progression (219)

doi: 10.1016/j.gene.2017.07.074 108

Lactobacillus fermentum ME-3 produces another powerful antioxidant enzyme called manganese superoxide dismutase (MnSOD). MnSOD is the primary antioxidant enzyme in mitochondria which are the energy-producing sites within cells

Furthermore, as NAC is readily oxidized to its disulfide di-NAC, which has oxidative rather than reductive effects, the source and form of NAC taken may cause great variability in the response to treatment and should be taken into account [9]
