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67,179 This second phase of acute focal TBI is complete about a month after the insult, when the mature lesion, composed of the central fibrotic scar (fully devoid of neural elements) and the surrounding astroglial limitans border have formed
These damaged cells release harmful inflammatory signals, disrupting the delicate environment needed for healthy brain function
Additionally, GABAergic neuron excitability in PD is increased at the dopaminergic D2 receptor but decreased at the D1 receptor, indicating an imbalance between the direct and indirect pathways
& Marnett, L
