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1)):S213S219

NASH is hallmarked by hepatocellular necrosis, lobular inflammation and often fibrosis

Embodiment 222 A method of expanding a population of genetically engineered T cells in a mammal diagnosed with cancer, said method comprising administering to said mammal administering to said mammal a T cell genetically modified to express a chimeric antigen receptor (CAR) according to any one of embodiments 201- 205, wherein the administered genetically engineered T cell produces a population of progeny T cells in the human

For linearity with a thiocholine concentrations, dilute solutions bearing different concentrations (0.125, 0.25, 0.5 and 1.0 mmol/L) of thiocholine were prepared by diluting indicated stock thiocholine solution with distilled water