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[DOI] [PMC free article] [PubMed] [Google Scholar] 161.Shin J.W., Chun K.-S., Kim D.-H., Kim S.-J., Kim S.H., Cho N.-C., Na H.-K., Surh Y.-J

The stable property of carboplatin is a mixed blessing: once uptake of the drug occurs, its retention half-life is considerably longer than cisplatin, but it is also this inertness that causes carboplatin to go right through the human body, and up to 90% of the carboplatin given can be recovered in urine (Go and Adjei, 1999)

interaction between alcohol metabolism byproducts and other cell components, resulting in the formation of harmful compounds (i.e., adducts)

Pascoli V, Valjent E, Corbille AG, et al
