glutathione pathway brain Frontiers Frontiers | The roles of

It enhances HIF-1 expression, which drives cell growth, extracellular matrix production and cell migration (Wilson, 2018)

Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism (Mari et al., 2013)

Nature (2000) 407(6801):24957