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FOXC1 and POU2F1 protein expression across NPM1 -mutated AML-8 subtypes (n = 72 patients)

1 O 2 was generated in C@P + 8 mM GSH group, C@PA + 8 mM GSH group, and SeC@PA + 8 mM GSH group, RNS was produced in C@PA + 8 mM GSH group, and SeC@PA + 8 mM GSH group, while OH was only generated in SeC@PA + 8 mM GSH group, and the intensity of each RS had no obvious difference (Supplementary Fig

The karyotype was male (46 XY) and the ultrasonography confirmed the absence of testes in the scrotum, suggesting a potential case of cryptorchidism

These effects are mediated in part by stress-responsive transcription factors that coordinate the expression of genes involved in GSH metabolism and redox control