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Among the seleno-containing isoforms, GPx1-4 are found in mammals and GPx6 only in humans [38]
Oxygen (O 2 ) plays a major role in the formation of ROS because O 2 has unpaired electrons (represented by single dots)
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reported side effects include: headache hypertension Drug Interactions: may cause hypertension if given with other pressor agents References: Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)
