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Therefore, vitamin B12 is thought as safe and non-toxic, although its still always best to stay with the suggested quantity and not take big dosages of any supplement without speaking with a doctor first
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A couple of studies found no benefits of B12 for lowering homocysteine in HD patients, one used oral B12, 2000 g three times per week for 6 weeks, 55 the other used methyl-B12 i.m

doi:10.1016/j.ejphar.2020.173368 Yilmaz H, Sahin S, Sayar N, et al
