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50 For symptomatic deficiency (box 1) caused by insufficient dietary intake, intramuscular B 12 therapy is usually initiated with the aim of progressing to oral supplements once symptoms have resolved

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The underlying pathogenesis reflects a complex interplay between viral activity and the host immune response, driving progressive liver injury that can ultimately lead to serious complications such as cirrhosis and hepatocellular carcinoma (495)

The protein bands on the PVDF membranes were then visualized using an enhanced chemiluminescence (ECL) kit (Thermo Fisher Scientific Inc., Shanghai, China)