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This aligns with previous plasma metabolomics profiles observed in GWS, where dysregulation of energy metabolism was evident
However, the success of the therapy largely depends on the metabolic compatibility between donor mitochondria and recipient cardiomyocytes

doi: 10.3389/fnins.2024.1275560, 234 YeL.LiW.TangX.XuT.WangG

Some of the changes may be due to random fluctuations in diet, or possibly due to seasonal effects (i.e., baseline values were measured in summer/fall (June-October) and final values in fall/winter (September to January)
