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synthesized by certain bacteria Although the intestinal flora of humans is able to synthesize vitamin B 12 , humans are not able to absorb bacteria-generated vitamin B 12 since the location of synthesis (the colon) is too distal from the location of absorption (the small intestine)

Highlights The scientists used a compound called 5-amino-1MQ to inhibit an enzyme called NNMT that plays a role in breaking down a precursor to NMN in the NAD+ synthesis pathway

The CAS number for AOD9604 is 386264-39-7, which uniquely identifies the compound for research and regulatory documentation

Moderate caloric restriction (15-20% below maintenance) supports AOD-9604 protocols without triggering metabolic adaptation or excessive muscle loss