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Taniki N, Nakamoto N, Chu PS, Mikami Y, Amiya T, Teratani T, Suzuki T, Tsukimi T, Fukuda S, Yamaguchi A, Shiba S, Miyake R, Katayama T, Ebinuma H, Kanai T (2018) Intestinal barrier regulates immune responses in the liver via IL-10-producing macrophages

Researchers study NNMT inhibition in the context of cellular NAD metabolism, methylation pathways, and metabolic regulation

A review in the Journal of Clinical Endocrinology and Metabolism found no evidence that HCG helps with weight loss [2]

It exhibits an IC 50 of approximately 1 M for NNMT inhibition 4 , with favorable pharmacokinetic properties
