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epigenetics is defined as the study of changes in the expression and regulation of genes does not involved in changes in the DNA sequence which can be classified into DNA methylation, histone modification, miRNA, genomic imprinting and chromosome remodeling [2, 3]

doi: 10.1186/1472-6882-13-253

In experimental models: KPV is linked to inflammatory signaling modulation BPC-157 is associated with tissue-level structural responses TA1 is examined in relation to immune coordination and signaling balance These roles are not isolated but instead contribute to a broader system in which cellular environment, structural integrity, and immune signaling operate together