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100 Forty-seven percent of patients in the NAC group were much or very much improved, compared with 19% in the placebo group

AQ-QI and DEAQ-QI showed a comparable doseresponse ( Figure 2 )

Here we review a dozen promising IN peptide therapeutics in preclinical and clinical development for neurodegenerative (Alzheimers, Parkinsons), neuropsychiatric (depression, PTSD, schizophrenia), and neurodevelopmental disorders (autism), with insulin, NAP (davunetide), IGF-1, PACAP, NPY, oxytocin, and GLP-1 agonists prominent among them

The bHLH TFs were reported to bind at the conserved E-box DNA binding (CANNTG) motif (Toledo-Ortiz et al., 2003)