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The expression of claudin-2 and claudin-15 is primarily restricted to crypt epithelia in both rodents and humans

Unlike standard cytoprotective agents that exhibit only prophylactic effectiveness (shared limitation of activity) [41,42,43,44,45,46,47,48], BPC 157 represents a prototype of a more effective class of cytoprotective agents with both prophylactic and therapeutic ability [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]

It's a key reason why many, including myself, find that consistent weekly shots make a remarkable difference in how we feel

Supplements are a practical way for some people to ensure they meet their daily vitamin B12 requirements