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Selenium, for example, enhances antioxidant mediators and upregulates genes associated with milk protein synthesis ( 3 administration enhances insulin sensitivity, energy metabolism, and hepatic IGF-1 synthesis, thereby promoting its transfer to the mammary gland (3638) provide a mechanistic basis for the elevated IGF levels and greater milk yield we recorded

Presumably, this is due to the low placental transfer, i.e., of certolizumab pegol, with suggested comparable safety for etanercept [80]

doi: 10.1136/acupmed-2017-011491 116 LiuWWangXZhengYShangGHuangJTaoJet al

It is reasonable to think that a higher intake of antioxidants than those recommended by the RDA may help to support the immune system of populations with high stress or exposure to environmental pollution, and this may include astronauts