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ALS patients present with atrophy of the spinal cord, often with gray and white matter in the brain, and usually die within 35 years after the onset of clinical symptoms
It was earlier demonstrated in cell lines that the binding of GSTP1 to JNK1 is a crucial step in apoptosis repression 33,35
Glutamate is the most abundant excitatory neurotransmitter in the brain, while glutathione is a powerful antioxidant and detoxifier