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An early study showed that intravenous or intracerebroventricular obestatin had no effects on pituitary hormone release (GH, prolactin, ACTH and TSH) in male rats (116), consistent with the fact that the obestatin receptor GPR39 is not expressed in the pituitary (115,117,118)

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However, SAH demonstrates activity solely in enzyme-based biochemical assays

Multiple sclerosis, in StatPearls treasure (Island, FL: StatPearls Publishing