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As expected, these signals were sensitive to imatinib treatment only in WT-Bcr-Abl-32D cells but not T315I-Bcr-Abl-32D cells, while ponatinib 27 treatment abolished these signals in both cell lines (Supplementary Fig
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The organoids showed the presence of continuous luminal structures, reconstructed in 3D, with a diameter of 8 m
coli and most of the pathogenic GGTs represents a functional similarity to mammalian GGTs
