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GEMMS involve targeted modifications of the murine genome, such as gene knockout (deletion), knock-in (mutagenesis), or transgenic overexpression, enabling the study of tumor biology within an intact immune system and native tissue microenvironment

The long-term effects of marijuana use are as follows: Cognitive Impairment : Chronic marijuana use impairs memory, learning, and attention

43 Therefore, inducing apoptosis in M1 macrophages or reprogramming them to the M2 phenotype has emerged as an important therapeutic strategy

Gold nanoparticles reduce high glucose-induced oxidative-nitrosative stress regulated inflammation and apoptosis via tuberin-mTOR/NF-B pathways in macrophages