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ABT-263 (Chang et al., 2016) and ABT-737 (Yosef et al., 2016) target the BCL-2/W/XL family of anti-apoptotic guardians (See also Fig

Alternatively, there are immunotherapies directed at surface antigens specifically upregulated in senescent cells (seno-antigens), including chimeric antigen receptor (CAR) therapies and senolytic vaccines
[4] Without vitamin K, blood coagulation is seriously impaired, and uncontrolled bleeding occurs
