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doi: 10.3390/molecules24142546

5.2.2 Ameliorating inflammation and oxidative stress Dihydroartemisinin reduces the expression of TGF-1, a key factor in fibrosis, and inhibits the activation of JAK2 and STAT3, thereby decreasing the expression of the inflammatory factors, such as IL-1, IL-6, TNF-, and chemokine ligand 3, and reducing the infiltration of inflammatory cells (You et al., 2022)

MASLD is the most common chronic liver disease and comprises histopathological disorders that range from the accumulation of triglycerides in the liver (steatosis) to non-alcoholic steatohepatitis (MASH) characterized by the presence of inflammation and fibrosis in the liver [14]

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