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66 To counter the harmful effects of ROS, ocular cells are equipped with a complex antioxidant defense system

Although a great many chronic, inflammatory diseases are recognised as having an oxidative stress component (223) , the history of treating them with antioxidants such as ascorbate has largely been a litany of failure, with the treatment arm often even giving worse prognoses than the placebo (6,223,489501)

doi: 10.1038/s41419-021-03520-2
