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Involvement of PGC-1 in the formation and maintenance of neuronal dendritic spines
in particular, data from HNE cells cultured at ALI have been shown to correlate strongly with in vivo clinical responses to CFTR modulators, serving as an effective pre-clinical tool to predict patient-specific drug efficacy
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These findings strongly support the inhibitory role of EGR1 in the growth of various tumors, further supporting our data and emphasizing the anti-tumor role of EGR1
