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It is required for life and is safe to use

Additionally, emerging mitochondria-targeted compounds, such as SS-31 (elamipretide) and MitoQ, have demonstrated preclinical efficacy in reducing oxidative damage and restoring mitochondrial function in neuronal models of depression and E2 deficiency (139)

At the time of this writing there is no strong or clinical studies indicating whether Hydroxocobalamin or Methylcobalamin are more beneficial compared to each other as a supplement

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