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Coffin et al., 8)

commonly called glutathione reductase) and thioredoxin reductases are reduced

However, under obesity, marked shifts occur in the levels and activities of these vital enzymes, particularly within adipose tissue

Although elegant and effective for yeast ( Saccharomyces cerevisiae ) grown in specifically controlled media, global isotopic labeling is prohibitively expensive, time-consuming, and practically inapplicable to complex mammalian cell culture models or clinical samples
