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In plant cell, mitochondria, chloroplasts and peroxisomes are the main locations of ROS generation 5

10.1016/S0009-2797(97)00149-X
In particular, upon administration in mice, only the mono-glutathionylated adducts were not toxic to kidneys, while a correlation was recorded between the number of glutathione substitutions and the nephrotoxicity observed [83]

Despite much focus on the intratumor microbiota, their origins remain inadequately understood
