glutathione reductase and selenium The peroxidase family: Discoveries mechanism The Role of Selenium ,

Activation depends on the type of DNA damage: ATM is recruited to DNA double-strand breaks (DSBs) induced by agents such as ionizing radiation (IR), whereas ATR is recruited to sites of replication protein A (RPA)-coated single-stranded DNA (ssDNA)

Further clinical assessments were performed biweekly (at weeks 2, 4, 6, 8, and 10)

[DOI] [PubMed] [Google Scholar] 315.Schnabel R

The obtained results are typical for old animals (Goshovska et al., 2009) and indicate calcium overload of cardiomyocytes, energy deficit, and intensification of oxidative metabolism and support the data about the excessive formation of ROS in aged rat heart mitochondria (Table 2)