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10.1111/cns.12789 36 SeguraB.StrafellaA

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Can L-Carnitine help with diabetes

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Neurochem Int 61:100107 Nasca C, Xenos D, Barone Y, Caruso A, Scaccianoce S, Matrisciano F, Battaglia G, Mathe AA, Pittaluga A, Lionetto L, Simmaco M, Nicoletti F (2013) l-Acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors

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The "timing hypothesis" or "critical window" hypothesis, now supported by substantial mechanistic and clinical data, proposes that estrogen's cardiovascular protective effects are contingent on initiating therapy while vascular endothelium remains estrogen-responsive, generally within ten years of menopause onset or before age 60 [8]

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