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It is produced naturally by the liver and involved in many processes in the body, mainly detoxification but also plays a role in tissue building and repair, making chemicals and proteins, and for immune system support

Using NHANES data, Liu et al

The physiological response to exogenous testosterone is further modulated by individual genetic variability, particularly polymorphisms of the androgen receptor gene, which contribute to substantial interindividual differences in efficacy and adverse effect profiles (12)

Bosch M, Franklin-Tong VE
