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Description
Further work will be needed to characterize the physiological contexts in which this pathway is employed versus the ACLY- or ACSS2-dependent routes to supply acetyl-CoA for lipid synthesis and chromatin modification

Androgens/AR and mitochondria may be involved in the exercise-induced effects on glucose and lipid metabolism, considering the regulatory role of exercise in both androgens/AR and mitochondria

Clin Neurol Neurosurg 2005

Weight of evidence: Overall evidence is Low, some RCTs document benefits for social communication and internalizing symptoms, but findings are inconsistent across age groups and severity levels, and no study integrates redox biomarkers to confirm mechanistic effects
